SCHEMBL27650692

SCHEMBL27650692

O=CC(=O)c1cccn1-c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
APEX1 P27695 1/20 0.43
MAPK1 P28482 2/20 0.37
NPC1 O15118 1/20 0.37
HTR7 P34969 3/20 0.37
HCAR1 Q9BXC0 1/20 0.36
NOTUM Q6P988 1/20 0.35
BCHE P06276 1/20 0.35
GSK3B P49841 1/20 0.35
NR4A1 P22736 1/20 0.35
NR4A2 P43354 1/20 0.35
NR4A3 Q92570 1/20 0.35
CDC25B P30305 1/20 0.35
PLK1 P53350 1/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.34
HTR3E A5X5Y0 1/20 0.34
HTR3B O95264 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30882318 0.83 POLB (0.63) POLBL3MBTL1TDP1APEX1MAPK1
SCHEMBL27986571 0.80 TDP1 (0.46) POLBL3MBTL1TDP1APEX1MAPK1
SCHEMBL27594558 0.76 AR (0.48) POLBL3MBTL1TDP1APEX1NPC1
SCHEMBL28778099 0.75 GPR84 (0.41) POLBL3MBTL1TDP1APEX1MAPK1
SCHEMBL27483362 0.74 ATM (0.52) POLBL3MBTL1TDP1APEX1MAPK1
SCHEMBL29286704 0.69 MAPT (0.42) POLBL3MBTL1TDP1APEX1HCAR1
SCHEMBL13325607 0.68 NPC1 (0.44) POLBMAPK1NPC1HTR7HCAR1
SCHEMBL20918913 0.68 POLB (0.50) POLBTDP1MAPK1NPC1HTR7
SCHEMBL27603684 0.68 LMNA (0.50) POLBL3MBTL1TDP1APEX1MAPK1
SCHEMBL29006051 0.68 ALDH1A1 (0.42) POLBL3MBTL1TDP1APEX1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108884031-A Pyrrole-2,5-diones derivative, its agronomy composition with Fungicidally active and application thereof 伊萨格罗股份公司 2018-11-23 CN disclosed
CN-101160049-B Spiroketal-substituted cyclic ketoenols BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-05-11 CN disclosed
CN-102781227-B By the method using herbicide treatment to improve soybean plant strain output BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-04-27 CN disclosed
CN-105248428-A Herbicide combinations comprising a herbicide of the class of the diaminos-triazines BAYER CROPSCIENCE AG 2016-01-20 CN disclosed
CN-105104414-A Active substance combinations that have nematicidal, insecticidal, and fungicidal properties and are based on trifluorobutenyl compounds BAYER CROPSCIENCE AG 2015-12-02 CN disclosed
CN-102550570-B Active substance combinations that have nematicidal, insecticidal, and fungicidal properties and are based on trifluorobutenyl compounds MAKHTESHIM CHEM WORKS LTD 2015-07-08 CN disclosed
CN-101817811-B 1,3-dimethylbutyl carboxanilides for controlling undesirable micro-organisms BAYER CROPSCIENCE AG 2014-09-03 CN disclosed
CN-102781241-B Method of improving plant yield of soybeans by treatment with herbicides Bayer intellectual property co ltd 2014-08-13 CN disclosed
CN-103755716-A Spiroketal-substituted cyclic ketoenols BAYER CROPSCIENCE AG 2014-04-30 CN disclosed
CN-101495448-B alkoxyalkyl-substituted cyclic ketoenols BAYER CROPSCIENCE AG 2014-02-19 CN disclosed
CN-102558116-A 2-halofuryl/thienyl-3-carboxamides BAYER CROPSCIENCE AG 2012-07-11 CN disclosed
CN-1774432-A Oxatiincarboxamidas BAYER CROPSCIENCE AG (DE) 2006-05-17 CN disclosed