SCHEMBL27651007

SCHEMBL27651007

C=Cc1ccccc1Nc1ccc(-c2ccc(N)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.53
KDM4E B2RXH2 3/20 0.53
HSD17B10 Q99714 2/20 0.53
ALOX15 P16050 2/20 0.53
TP53 P04637 2/20 0.53
APP P05067 1/20 0.53
HPGD P15428 1/20 0.53
SNCA P37840 1/20 0.53
BLM P54132 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
ALDH1A1 P00352 7/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPK1 P28482 1/20 0.46
CYP3A4 P08684 3/20 0.46
HTT P42858 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
ALOX12 P18054 1/20 0.46
TDP1 Q9NUW8 5/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24292255 0.80 MAPK13 (0.40) MAPTKDM4EHSD17B10ALOX15TP53
SCHEMBL291979 0.80 MAPT (0.50) MAPTKDM4EHSD17B10ALOX15TP53
SCHEMBL25502791 0.78 KDM4E (0.42) MAPTKDM4EHSD17B10ALOX15TP53
SCHEMBL31454751 0.75 MAPT (0.78) MAPTKDM4EHSD17B10ALOX15TP53
SCHEMBL31091224 0.75 ALDH1A1 (0.48) MAPTKDM4EBLMALDH1A1CYP3A4
SCHEMBL7004084 0.74 MAPT (0.58) MAPTKDM4EHSD17B10ALOX15TP53
SCHEMBL17794524 0.72 MAPT (0.56) MAPTKDM4EHSD17B10ALOX15TP53
SCHEMBL7007688 0.72 MAPT (0.86) MAPTKDM4EHSD17B10ALOX15TP53
SCHEMBL2478605 0.72 MAPT (0.86) MAPTKDM4EHSD17B10ALOX15TP53
SCHEMBL7011541 0.72 MAPT (0.77) MAPTKDM4EHSD17B10ALOX15TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1777629-A Electroactive polymers 3M INNOVATIVE PROPERTIES CO (US) 2006-05-24 CN disclosed