Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 4/20 | 0.61 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297256 | 0.89 | CDC7 (0.48) | CDC7DBF4KDM4EALDH1A1FNTA | |
| SCHEMBL10994239 | 0.86 | CDC7 (0.63) | CDC7DBF4KDM4EALDH1A1FNTA | |
| SCHEMBL28297258 | 0.85 | CDC7 (0.65) | CDC7DBF4KDM4EALDH1A1FNTA | |
| SCHEMBL15383553 | 0.84 | ALDH1A1 (0.62) | CDC7DBF4KDM4EALDH1A1TRPM8 | |
| SCHEMBL11272574 | 0.84 | RAB9A (0.54) | KDM4EALDH1A1ABCG2ABCC1LMNA | |
| SCHEMBL11250314 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1ABCG2LMNAMAPT | |
| SCHEMBL11259410 | 0.82 | GAA (0.60) | KDM4EALDH1A1ABCG2ABCC1LMNA | |
| SCHEMBL11296296 | 0.82 | ALDH1A1 (0.58) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL2085303 | 0.80 | CDC7 (0.73) | CDC7DBF4KDM4EALDH1A1TRPM8 | |
| SCHEMBL28297244 | 0.80 | CDC7 (0.65) | CDC7DBF4KDM4EALDH1A1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810071-A | A kind of miRNA biosynthesis inhibitor | 中国科学院成都生物研究所 | 2019-05-28 | — | — | CN | disclosed |
| EP-1400515-B1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | KOWA CO (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-1400515-A1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | Kowa Co., Ltd. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6472386-B1 | Cyclic diamine compound with 5-membered ring groups | KOWA CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| US-4558059-A | ANTI-PEPTIC ULCER AGNET | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-12-10 | — | — | US | disclosed |
| EP-0051409-B1 | 2-(SUBSTITUTED-PHENYL)-THIAZOLE DERIVATIVES SUITABLE FOR PEPTIC ULCER TREATMENT | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-03-21 | — | — | EP | disclosed |
| US-4363813-A | ANTIPEPTIC ULCER AGENT | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-12-14 | — | — | US | disclosed |
| EP-0051409-A1 | 2-(Substituted-phenyl)-thiazole derivatives suitable for peptic ulcer treatment | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-05-12 | — | — | EP | disclosed |