Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.63 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15383553 | 0.90 | ALDH1A1 (0.62) | CDC7DBF4KDM4EALDH1A1HPGD | |
| SCHEMBL289848 | 0.90 | KDM4E (0.55) | CDC7DBF4HTTKDM4EALDH1A1 | |
| SCHEMBL23417724 | 0.86 | CDC7 (0.56) | CDC7DBF4KDM4EALDH1A1HPGD | |
| SCHEMBL19523349 | 0.86 | XDH (0.60) | CDC7DBF4KDM4EALDH1A1HPGD | |
| SCHEMBL2765160 | 0.86 | CDC7 (0.61) | CDC7DBF4KDM4EALDH1A1HPGD | |
| SCHEMBL10994224 | 0.84 | LMNA (0.54) | CDC7DBF4KDM4EALDH1A1HPGD | |
| SCHEMBL2085303 | 0.84 | CDC7 (0.73) | CDC7DBF4KDM4EALDH1A1HPGD | |
| SCHEMBL28295522 | 0.83 | CDC7 (0.67) | CDC7DBF4KDM4EALDH1A1TRPM8 | |
| SCHEMBL14345641 | 0.83 | GAA (0.54) | CDC7DBF4KDM4EALDH1A1HPGD | |
| SCHEMBL2881560 | 0.82 | CDC7 (0.63) | CDC7DBF4KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558059-A | ANTI-PEPTIC ULCER AGNET | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-12-10 | — | — | US | disclosed |
| EP-0051409-B1 | 2-(SUBSTITUTED-PHENYL)-THIAZOLE DERIVATIVES SUITABLE FOR PEPTIC ULCER TREATMENT | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-03-21 | — | — | EP | disclosed |
| EP-0051409-A1 | 2-(Substituted-phenyl)-thiazole derivatives suitable for peptic ulcer treatment | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-05-12 | — | — | EP | disclosed |