Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.39 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630399 | 0.83 | ALDH1A1 (0.40) | ALDH1A1PKMHSPA5L3MBTL1MAPT | |
| SCHEMBL1133747 | 0.83 | ALDH1A1 (0.40) | ALDH1A1PKMHSPA5L3MBTL1MAPT | |
| SCHEMBL13370728 | 0.79 | ALDH1A1 (0.41) | ALDH1A1PKML3MBTL1MAPTHTT | |
| SCHEMBL8701139 | 0.77 | PKM (0.38) | ALDH1A1PKMHSPA5L3MBTL1MAPT | |
| SCHEMBL27585045 | 0.75 | PKM (0.39) | ALDH1A1PKMHSPA5L3MBTL1MAPT | |
| SCHEMBL27641755 | 0.74 | ALDH1A1 (0.41) | ALDH1A1PKML3MBTL1MAPTHTT | |
| SCHEMBL5679261 | 0.73 | DPP8 (0.40) | ALDH1A1HSPA5HSPA2DPP8DPP9 | |
| SCHEMBL6056845 | 0.72 | HSPA5 (0.60) | ALDH1A1PKMHSPA5HSPA2LMNA | |
| SCHEMBL7415644 | 0.72 | HSPA5 (0.60) | ALDH1A1PKMHSPA5HSPA2LMNA | |
| Hydrochloric Acid SCHEMBL7417556 | 0.71 | HSPA5 (0.59) | ALDH1A1PKMHSPA5HSPA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102186825-A | Aryl gpr120 receptor agonists and uses thereof | METABOLEX INC | 2011-09-14 | — | — | CN | disclosed |
| CN-1993320-A | Sulfonyl compounds as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1 | MERCK & CO INC (US) | 2007-07-04 | — | — | CN | disclosed |
| CN-1938286-A | Diaryltriazoles as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1 | MERCK & CO INC (US) | 2007-03-28 | — | — | CN | disclosed |
| CN-1870990-A | Fused phenylalanine derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes | MERCK & CO INC (US) | 2006-11-29 | — | — | CN | disclosed |
| CN-1845731-A | Combination therapy for glycaemic control | PROSIDION LTD (GB) | 2006-10-11 | — | — | CN | disclosed |