Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27852212 | 0.81 | MMP1 (0.41) | MMP1MMP2MMP9MMP12ALOX5 | |
| SCHEMBL41616 | 0.81 | MMP1 (0.43) | MMP1MMP2MMP9MMP12SLC1A3 | |
| SCHEMBL3399442 | 0.81 | MMP1 (0.43) | MMP1MMP2MMP9MMP12SLC1A3 | |
| SCHEMBL7620751 | 0.79 | SLC15A1 (0.37) | MMP1MMP2MMP9MMP12SLC1A3 | |
| SCHEMBL27711054 | 0.78 | MMP1 (0.41) | MMP1MMP2MMP9MMP12RAB9A | |
| SCHEMBL1897993 | 0.78 | MMP1 (0.41) | MMP1MMP2MMP9MMP12SLC1A3 | |
| SCHEMBL8228297 | 0.77 | MMP1 (0.45) | MMP1MMP2MMP9MMP12ALOX5 | |
| SCHEMBL29159324 | 0.77 | MMP1 (0.40) | MMP1MMP2MMP9MMP12SLC1A3 | |
| SCHEMBL27458824 | 0.76 | MMP1 (0.44) | MMP1MMP2MMP9MMP12ALOX5 | |
| SCHEMBL7780494 | 0.75 | DPP8 (0.48) | DPP8DPP9DPP7DPP4SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392718-B1 | IMPROVED NATIVE CHEMICAL LIGATION WITH THREE OR MORE COMPONENTS | GENEPROT INC (CH) | 2006-01-11 | — | — | EP | disclosed |