SCHEMBL27652255

SCHEMBL27652255

[CH2]Cc1cccc(-c2ccccc2O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
HPGD P15428 1/20 0.52
BCL2L1 Q07817 1/20 0.52
HSD17B10 Q99714 1/20 0.52
PTPN5 P54829 1/20 0.47
ESR2 Q92731 1/20 0.44
SELL P14151 3/20 0.41
SELP P16109 3/20 0.41
SELE P16581 2/20 0.41
HTR7 P34969 4/20 0.40
APP P05067 1/20 0.39
KDM1A O60341 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
BACE1 P56817 2/20 0.39
ALOX5 P09917 1/20 0.38
QPCT Q16769 1/20 0.38
QPCTL Q9NXS2 1/20 0.38
MMP3 P08254 1/20 0.38
KDR P35968 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20994110 0.83 ALDH1A1 (0.59) ALDH1A1HPGDBCL2L1HSD17B10PTPN5
SCHEMBL8607300 0.81 BCL2L1 (0.57) ALDH1A1HPGDBCL2L1HSD17B10PTPN5
SCHEMBL21257503 0.81 ALDH1A1 (0.52) ALDH1A1HPGDBCL2L1HSD17B10PTPN5
SCHEMBL2450409 0.81 ALDH1A1 (0.52) ALDH1A1HPGDBCL2L1HSD17B10PTPN5
SCHEMBL7570908 0.80 HPGD (0.71) ALDH1A1HPGDBCL2L1HSD17B10PTPN5
SCHEMBL29944266 0.80 HPGD (0.71) ALDH1A1HPGDBCL2L1HSD17B10PTPN5
SCHEMBL7033605 0.79 MMP3 (0.63) ALDH1A1HPGDBCL2L1HSD17B10PTPN5
SCHEMBL12305661 0.77 HTR7 (0.63) ALDH1A1HPGDBCL2L1HSD17B10PTPN5
SCHEMBL13218888 0.77 ALDH1A1 (0.47) ALDH1A1HPGDBCL2L1HSD17B10PTPN5
SCHEMBL27999724 0.77 SELP (0.60) ALDH1A1HPGDBCL2L1HSD17B10PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100506782-C 3-(2-alkoxycarbonyloxy-phenyl) acrylic acid esters and their use as precursors for the delivery of olfactory compounds GIVAUDAN SA (CH) 2009-07-01 CN disclosed
CN-1918108-A 3-(2-alkoxycarbonyloxy-phenyl) acrylic acid esters and their use as precursors for the delivery of olfactory compounds GIVAUDAN SA (CH) 2007-02-21 CN disclosed