Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 2/20 | 0.35 |
| ▸ | PGK2 | P07205 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | NAT1 | P18440 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073513 | 0.83 | UNG (0.48) | UNGALDH1A1SRCTRIM24TRIM33 | |
| SCHEMBL2937253 | 0.83 | ALDH1A1 (0.48) | UNGALDH1A1SRCTRIM24TRIM33 | |
| SCHEMBL8127721 | 0.81 | UNG (0.43) | UNGALDH1A1SRCTRIM24TRIM33 | |
| SCHEMBL2642178 | 0.78 | UNG (0.48) | UNGALDH1A1SRCTRIM24TRIM33 | |
| SCHEMBL30265731 | 0.77 | LMNA (0.55) | UNGALDH1A1SRCTRIM24TRIM33 | |
| SCHEMBL27346087 | 0.77 | ALDH5A1 (0.44) | UNGALDH1A1SRCTRIM24TRIM33 | |
| SCHEMBL27555156 | 0.76 | ALDH1A1 (0.41) | UNGALDH1A1SRCTRIM24TRIM33 | |
| SCHEMBL21310006 | 0.76 | UNG (0.42) | UNGALDH1A1SRCTRIM24TRIM33 | |
| SCHEMBL727874 | 0.75 | TYR (0.56) | UNGALDH1A1SRCTRIM24TRIM33 | |
| SCHEMBL4950119 | 0.75 | ALDH1A1 (0.48) | UNGALDH1A1SRCTRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1914173-A | Quinolines useful in treating cardiovascular disease | WYETH CORP (US) | 2007-02-14 | — | — | CN | disclosed |