Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5629171 | 0.79 | KDM4E (0.46) | RAB9ANPC1RXFP1KDM4EPOLB | |
| SCHEMBL4543263 | 0.79 | CYP1A2 (0.56) | RAB9ANPC1RXFP1KDM4EPOLB | |
| SCHEMBL15305786 | 0.79 | KDM4E (0.46) | RAB9ANPC1RXFP1KDM4EPOLB | |
| SCHEMBL14298343 | 0.79 | L3MBTL1 (0.54) | RAB9ANPC1RXFP1KDM4EPOLB | |
| SCHEMBL23015811 | 0.79 | KDM4E (0.43) | RAB9ANPC1RXFP1KDM4EPOLB | |
| SCHEMBL30421382 | 0.79 | CYP1A2 (0.64) | RAB9ANPC1RXFP1KDM4EPOLB | |
| SCHEMBL757416 | 0.78 | AURKA (0.47) | RAB9ANPC1RXFP1KDM4EPOLB | |
| SCHEMBL29768000 | 0.77 | ATR (0.46) | RAB9ANPC1 | |
| SCHEMBL22186826 | 0.76 | KDM4E (0.69) | RAB9ANPC1RXFP1KDM4EPOLB | |
| SCHEMBL2712669 | 0.75 | KDM4E (0.43) | RAB9ANPC1RXFP1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100424083-C | Pyrimidine derivative compound and its preparing method | GUANGXI NAT UNIV (CN) | 2008-10-08 | — | — | CN | disclosed |
| CN-1935805-A | Pyrimidine derivative compound and its preparing method | GUANGXI NAT UNIV (CN) | 2007-03-28 | — | — | CN | disclosed |