SCHEMBL4543263

SCHEMBL4543263

CC(=O)Nc1ccnc(NC(C)=O)n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.56
AURKA O14965 3/20 0.48
KDM4E B2RXH2 3/20 0.47
LMNA P02545 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPK8 P45983 1/20 0.46
MEN1 O00255 1/20 0.46
PRNP P04156 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46
HSP90AA1 P07900 1/20 0.46
HSP90AB1 P08238 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
IDH1 O75874 1/20 0.45
AURKB Q96GD4 1/20 0.45
CDK4 P11802 1/20 0.45
CCNE1 P24864 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15305788 0.83 HRH4 (0.52) CYP1A2KDM4ELMNAL3MBTL1MAPK8
SCHEMBL757416 0.83 AURKA (0.47) CYP1A2AURKAKDM4ELMNAL3MBTL1
SCHEMBL14298343 0.81 L3MBTL1 (0.54) CYP1A2KDM4EL3MBTL1MEN1PRNP
SCHEMBL5629171 0.81 KDM4E (0.46) CYP1A2KDM4ELMNAL3MBTL1MEN1
SCHEMBL15305786 0.81 KDM4E (0.46) CYP1A2KDM4ELMNAL3MBTL1MEN1
SCHEMBL20068960 0.81 SORT1 (0.54) CYP1A2KDM4ELMNAL3MBTL1MAPK8
SCHEMBL5632488 0.81 CYP1A2 (0.53) CYP1A2KDM4ELMNAL3MBTL1MAPK8
SCHEMBL19546161 0.81 CFD (0.44) CYP1A2AURKAKDM4EL3MBTL1MEN1
SCHEMBL19546160 0.80 HRH4 (0.40) CYP1A2AURKAKDM4EMAPK8MEN1
SCHEMBL29013232 0.79 CYP1A2 (0.51) CYP1A2KDM4ELMNAL3MBTL1MAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871314-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2014-10-28 US disclosed
US-20130266744-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND FUJIFILM CORPORATION (JP) 2013-10-10 US disclosed
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed