Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825292 | 1.00 | USP2 (0.38) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL27844231 | 0.84 | — | — | |
| SCHEMBL6247036 | 0.82 | USP2 (0.39) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL28093337 | 0.81 | FAAH (0.42) | LMNAKDM4E | |
| SCHEMBL4587134 | 0.80 | USP2 (0.39) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL25394043 | 0.79 | LMNA (0.36) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL17076565 | 0.79 | USP2 (0.34) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL5960037 | 0.78 | USP2 (0.42) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL7025484 | 0.78 | USP2 (0.47) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL28449969 | 0.78 | USP2 (0.47) | USP2SLCO1B1LMNAL3MBTL1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108064173-A | Partial insulin receptor agonists | 默沙东公司 | 2018-05-22 | — | — | CN | claimed |
| CN-102365025-A | Conjugate-based systems for controlled drug delivery | SMARTCELLS INC | 2012-02-29 | — | — | CN | claimed |
| CN-102341409-A | Crystalline insulin-conjugates | SMARTCELLS INC | 2012-02-01 | — | — | CN | claimed |
| CN-108064173-A | Partial insulin receptor agonists | 默沙东公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-105792852-A | Glucose-responsive insulin conjugates | 默沙东公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-105753965-A | Conjugate Based Systems For Controlled Drug Delivery | 斯马特塞尔斯公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-102365025-A | Conjugate-based systems for controlled drug delivery | SMARTCELLS INC | 2012-02-29 | — | — | CN | disclosed |
| CN-102341409-A | Crystalline insulin-conjugates | SMARTCELLS INC | 2012-02-01 | — | — | CN | disclosed |
| CN-1934276-A | Protein expression yield enhancement in cell-free protein synthesis systems by addition of antifoam agents | UNIV LELAND STANFORD JUNIOR (US) | 2007-03-21 | — | — | CN | disclosed |