Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374174 | 0.83 | TAS2R14 (0.50) | ALKBH5TTRSMN1; SMN2TAS2R14RARB | |
| SCHEMBL29528380 | 0.83 | TAS2R14 (0.50) | ALKBH5TTRSMN1; SMN2TAS2R14RARB | |
| Methylpiperazine SCHEMBL27675362 | 0.82 | HDAC1 (0.45) | TTRSMN1; SMN2KDM5CKDM4COPRD1 | |
| SCHEMBL16207486 | 0.81 | HPGD (0.52) | — | |
| Methylpiperazine SCHEMBL27675357 | 0.81 | HPGD (0.47) | TTRSMN1; SMN2KDM5CKDM4COPRD1 | |
| SCHEMBL580653 | 0.77 | TTR (0.55) | TTRRARBGAA | |
| SCHEMBL23166542 | 0.76 | TAS2R14 (0.45) | ALKBH5TAS2R14RARBADCY8ADCY1 | |
| 4-Methylbenzoic Acid SCHEMBL7098695 | 0.75 | ALDH1A1 (0.59) | SMN1; SMN2OPRD1 | |
| 4-Methylbenzoic Acid SCHEMBL27796615 | 0.74 | ALDH1A1 (0.57) | SMN1; SMN2OPRD1 | |
| 4-Methylbenzoic Acid SCHEMBL27775567 | 0.74 | ALDH1A1 (0.57) | SMN1; SMN2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972917-B | Aminopyrimidine compounds and their salts, process for preparation and pharmaceutical use thereof | PIAOYANG SUN | 2010-08-25 | — | — | CN | disclosed |
| CN-1939910-A | Amino-metadiazine compound and its salt, its preparation and pharmaceutical use | SUN PIAOYANG (CN) | 2007-04-04 | — | — | CN | disclosed |