Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpiperazine SCHEMBL27675357 | 0.84 | HPGD (0.47) | KMT2AMEN1SMN1; SMN2LMNAHTT | |
| Methylpiperazine SCHEMBL27655409 | 0.82 | ALKBH5 (0.43) | SMN1; SMN2KDM5CKDM4CTTROPRD1 | |
| SCHEMBL503345 | 0.81 | HDAC1 (0.63) | HDAC1HDAC6KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL24746207 | 0.79 | KMT2A (0.54) | HDAC1HDAC6KMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL6563896 | 0.79 | HDAC1 (0.61) | HDAC1HDAC6KMT2AMEN1SMN1; SMN2 | |
| 4-Methylbenzoic Acid SCHEMBL7098695 | 0.79 | ALDH1A1 (0.59) | KMT2AMEN1SMN1; SMN2LMNARAB9A | |
| Hydrochloric Acid SCHEMBL623790 | 0.78 | HPGD (0.55) | HDAC1HDAC6KMT2AMEN1LMNA | |
| 4-Methylbenzoic Acid SCHEMBL27775567 | 0.77 | ALDH1A1 (0.57) | KMT2AMEN1SMN1; SMN2RAB9AALDH1A1 | |
| 4-Methylbenzoic Acid SCHEMBL27796615 | 0.77 | ALDH1A1 (0.57) | KMT2AMEN1SMN1; SMN2RAB9AALDH1A1 | |
| Methylpiperazine SCHEMBL27761673 | 0.77 | GABRD (0.52) | KMT2AMEN1SMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972917-B | Aminopyrimidine compounds and their salts, process for preparation and pharmaceutical use thereof | PIAOYANG SUN | 2010-08-25 | — | — | CN | disclosed |
| CN-1939910-A | Amino-metadiazine compound and its salt, its preparation and pharmaceutical use | SUN PIAOYANG (CN) | 2007-04-04 | — | — | CN | disclosed |