Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.38 |
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655527 | 0.90 | KDM4E (0.52) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL27655553 | 0.90 | KDM4E (0.40) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL27655435 | 0.85 | ACHE (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL27655438 | 0.84 | PDE5A (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL27655593 | 0.83 | ESR1 (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL27675464 | 0.81 | PDE4A (0.45) | ALDH1A1CYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL27655434 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL27655551 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL27675509 | 0.81 | GAA (0.48) | KDM4EALDH1A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL5123345 | 0.78 | ESR1 (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1875023-A | Use of thienopyrimidines | MERCK PATENT GMBH (DE) | 2006-12-06 | — | — | CN | disclosed |