Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.41 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | PDE11A | Q9HCR9 | 5/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655435 | 0.94 | ACHE (0.42) | KDM4EALDH1A1LMNAHPGDSTAT3 | |
| SCHEMBL27675471 | 0.93 | KDM4E (0.43) | PDE5ABCDIN3DKDM4EALDH1A1LMNA | |
| SCHEMBL27675558 | 0.86 | ESR1 (0.46) | PDE5ABCDIN3DPDE11A | |
| SCHEMBL27675479 | 0.85 | PDE11A (0.41) | PDE5APDE11A | |
| SCHEMBL27675451 | 0.85 | GAA (0.43) | KDM4EALDH1A1LMNAHPGDSTAT3 | |
| SCHEMBL27675511 | 0.84 | PDE5A (0.41) | PDE5ABCDIN3DPDE11A | |
| SCHEMBL27655596 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1LMNAHPGDSTAT3 | |
| SCHEMBL27655553 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1LMNAHPGDSTAT3 | |
| SCHEMBL6708284 | 0.83 | KDM4E (0.49) | PDE5ABCDIN3DKDM4EALDH1A1LMNA | |
| SCHEMBL7187840 | 0.83 | KDM4E (0.45) | PDE5ABCDIN3DKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1875023-A | Use of thienopyrimidines | MERCK PATENT GMBH (DE) | 2006-12-06 | — | — | CN | disclosed |