Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655438 | 0.94 | PDE5A (0.41) | LMNASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL27675451 | 0.91 | GAA (0.43) | ACHELMNAAPPSMN1; SMN2KDM4E | |
| SCHEMBL27675471 | 0.87 | KDM4E (0.43) | LMNASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL27655596 | 0.85 | KDM4E (0.47) | LMNASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL27655553 | 0.85 | KDM4E (0.40) | LMNASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL27655448 | 0.84 | ESR1 (0.43) | ACHETSHRLMNAAPPSMN1; SMN2 | |
| SCHEMBL27675572 | 0.84 | ACHE (0.47) | ACHETSHRLMNAAPPSMN1; SMN2 | |
| SCHEMBL27675431 | 0.83 | ACHE (0.48) | ACHEAPPEGFRKDRKMT2A | |
| SCHEMBL27675464 | 0.82 | PDE4A (0.45) | ALDH1A1EGFRKMT2AMAPTGAA | |
| SCHEMBL5131031 | 0.80 | TSHR (0.48) | ACHETSHRLMNAAPPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1875023-A | Use of thienopyrimidines | MERCK PATENT GMBH (DE) | 2006-12-06 | — | — | CN | disclosed |