E1501

E1501

SCHEMBL27655685

CC(=O)OCc1ccccc1.[MgH2]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.96
TDP1 Q9NUW8 3/20 0.59
MAPK1 P28482 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
SLC6A2 P23975 1/20 0.59
SLC6A3 Q01959 1/20 0.59
KMT2A Q03164 1/20 0.59
IDH1 O75874 1/20 0.54
LMNA P02545 3/20 0.53
HCAR2 Q8TDS4 1/20 0.53
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
MAOB P27338 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E1501 SCHEMBL901210 0.98 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL14031569 0.98 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL43745 0.98 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL28201296 0.98 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL1256238 0.96 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL18954294 0.96 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL28928069 0.96 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL30579458 0.96 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL183528 0.96 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
E1501 SCHEMBL14334870 0.96 ALDH1A1 (0.96) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104023996-B For the method for the polydiene and polydiene copolymer that prepare the cold flow with reduction 株式会社普利司通 2017-10-24 CN disclosed
CN-104093751-B The method for preparing the polydiene and polydiene copolymer with the cold flow for reducing 株式会社普利司通 2017-05-31 CN disclosed
CN-104220466-B For the method preparing polydiene 株式会社普利司通 2016-09-21 CN disclosed
CN-103459402-B Lanthanide complexes catalyst and use its polymerization 株式会社普利司通 2016-09-07 CN disclosed
CN-103476780-B Lanthanide complex catalysts and polymerization methods using the same 株式会社普利司通 2016-08-17 CN disclosed
CN-104039843-B Prepare the method for polydiene BRIDGESTONE CO.,LTD. (JP) 2016-05-18 CN disclosed
CN-103183750-B Nickel-based catalyst composition BRIDGESTONE CO., LTD. (JP) 2016-03-30 CN disclosed
CN-103857704-B By the lactone containing shielded amino or the functionalized polymkeric substance of thiolactone BRIDGESTONE CO.,LTD. (JP) 2016-02-17 CN disclosed
CN-104945540-A Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORP 2015-09-30 CN disclosed
CN-103333275-B With the polymkeric substance of functionalized with nitrile compounds comprising protected amino BRIDGESTONE CO., LTD. (JP) 2015-07-29 CN disclosed
CN-102361887-A Polymers functionalized with nitrile compounds containing a protected amino group BRIDGESTONE CORP 2012-02-22 CN disclosed
CN-102245651-A New polymers and use thereof in preparation of high impact polymeric compositions BRIDGESTONE CORP 2011-11-16 CN disclosed
CN-102143980-A Polymers functionalized with imide compounds containing a protected amino group BRIDGESTONE CORP 2011-08-03 CN disclosed
CN-102124037-A Catalysts for preparing cis 1,4-polydienes BRIDGESTONE CORP 2011-07-13 CN disclosed
CN-101874044-A Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORP 2010-10-27 CN disclosed
CN-101563398-A Branched polymers and methods of synthesis and use thereof BRIDGESTONE CORP (JP) 2009-10-21 CN disclosed
CN-101525396-A The bulk polymerization used for producing polydiene BRIDGESTONE CORP 2009-09-09 CN disclosed
CN-101475655-A Process for producing polydienes BRIDGESTONE CORP (JP) 2009-07-08 CN disclosed
CN-101016355-A Functionalized polymers BRIDGESTONE CORP (JP) 2007-08-15 CN disclosed
CN-1970581-A Nickel-based catalyst composition BRIDGESTONE CORP (JP) 2007-05-30 CN disclosed