Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655782 | 0.92 | MAPT (0.41) | ALDH1A1KMT2AMEN1LMNARAB9A | |
| SCHEMBL27655745 | 0.90 | LMNA (0.35) | ALDH1A1KMT2ALMNARAB9ASMN1; SMN2 | |
| SCHEMBL15225754 | 0.84 | MAPK1 (0.50) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL2863214 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1LMNAGPR183 | |
| SCHEMBL27655750 | 0.80 | GRM1 (0.38) | ALDH1A1LMNAKDM4ETHRBHIF1A | |
| SCHEMBL2864940 | 0.80 | MAPT (0.48) | ALDH1A1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL2866292 | 0.80 | GRM3 (0.42) | ALDH1A1LMNARAB9ASMN1; SMN2POLB | |
| SCHEMBL2858385 | 0.79 | MAPT (0.55) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL2856092 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL2865742 | 0.78 | GRM3 (0.49) | ALDH1A1LMNARAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100567242-C | Hsp90 family protein blockers | KYOWA HAKKO KOGYO KK (JP) | 2009-12-09 | — | — | CN | disclosed |
| CN-1791568-A | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO KK (JP) | 2006-06-21 | — | — | CN | disclosed |