Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | GFER | P55789 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864940 | 0.93 | MAPT (0.48) | MAPK1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL2869162 | 0.90 | ME2 (0.53) | KDM4EMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL2864929 | 0.89 | MEN1 (0.52) | KDM4ERECQLTDP1MAPTALDH1A1 | |
| SCHEMBL2856092 | 0.87 | SMN1; SMN2 (0.47) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL2858385 | 0.87 | MAPT (0.55) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2859704 | 0.87 | SLC6A7 (0.53) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2863214 | 0.86 | ALDH1A1 (0.41) | MAPK1KDM4ERECQLTDP1MAPT | |
| SCHEMBL2866392 | 0.86 | FKBP1A (0.50) | KDM4EMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL2859146 | 0.86 | MAPT (0.47) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2854657 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1642880-B1 | HSP90 FAMILY PROTEIN INHIBITORS | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-09-04 | — | — | EP | claimed |