Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655996 | 0.90 | ALDH1A1 (0.40) | CHRM3ALDH1A1TP53LMNANPSR1 | |
| SCHEMBL5695482 | 0.88 | ALDH1A1 (0.39) | CHRM1CHRM3ALDH1A1TP53LMNA | |
| SCHEMBL3960632 | 0.88 | MTOR (0.41) | ALDH1A1TSHRGAA | |
| SCHEMBL27662339 | 0.88 | GRM5 (0.35) | CHRM1CHRM3ALDH1A1TP53KDM4E | |
| SCHEMBL27681882 | 0.86 | ALDH1A1 (0.41) | ALDH1A1TP53LMNANPSR1TSHR | |
| SCHEMBL3950290 | 0.86 | SLC6A9 (0.39) | ALDH1A1TP53SLC6A9KDM4EGAA | |
| SCHEMBL3957138 | 0.85 | BACE1 (0.39) | ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL27682053 | 0.82 | KDM4E (0.38) | ALDH1A1TP53SLC6A9KDM4EGAA | |
| SCHEMBL3955540 | 0.82 | CHRM3 (0.41) | CHRM1CHRM3HSD17B10ALDH1A1TP53 | |
| SCHEMBL27662418 | 0.82 | TSHR (0.47) | CHRM1CHRM3HSD17B10LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972920-A | Arylalkyl piperazine derivatives for the treatment of conditions ameliorated by monoamine reuptake including vasomotor symptoms | WYETH CORP (US) | 2007-05-30 | — | — | CN | disclosed |
| CN-1894226-A | Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use | WYETH CORP (US) | 2007-01-10 | — | — | CN | disclosed |