Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509170 | 0.82 | MAPT (0.47) | TP53SMN1; SMN2EPHX2L3MBTL1CNR1 | |
| SCHEMBL7055587 | 0.80 | RPA1 (0.51) | MARS1TP53KMT2AL3MBTL1MAPT | |
| SCHEMBL2360605 | 0.80 | UBE2N (0.48) | KMT2APOLBNPC1MAPTRAB9A | |
| SCHEMBL14152395 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2KMT2AMAPTALDH1A1 | |
| SCHEMBL181851 | 0.79 | GCGR (0.47) | MARS1EPHX2PDE5AL3MBTL1AURKA | |
| SCHEMBL8087729 | 0.78 | RXRA (0.40) | TP53SMN1; SMN2EPHX2L3MBTL1POLB | |
| SCHEMBL16875429 | 0.78 | RXRA (0.50) | L3MBTL1 | |
| SCHEMBL14150735 | 0.78 | KMT2A (0.64) | KMT2AL3MBTL1MAPT | |
| SCHEMBL31031032 | 0.76 | KMT2A (0.45) | TP53KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL182081 | 0.76 | MRGPRX4 (0.49) | TP53KMT2AAURKATPX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102869661-B | Anti-infective compounds | INSTITUT PASTEUR KOREA (KR) | 2015-08-05 | — | — | CN | disclosed |
| CN-102869661-A | Anti-infective compounds | PASTEUR INSTITUT KOREA | 2013-01-09 | — | — | CN | disclosed |
| CN-100467463-C | Pyrazolylindolyl derivatives as PPAR activators | HOFFMANN LA ROCHE (CH) | 2009-03-11 | — | — | CN | disclosed |
| CN-1930150-A | Pyrazolyl indolyl derivatives as PPAR activators | HOFFMANN LA ROCHE (CH) | 2007-03-14 | — | — | CN | disclosed |