Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | MARS1 | P56192 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28088814 | 0.86 | ALDH1A1 (0.51) | RPA1L3MBTL1ATMABCB11HDAC6 | |
| SCHEMBL23023945 | 0.83 | LMNA (0.51) | RPA1L3MBTL1TP53ALDH1A1HPGD | |
| SCHEMBL14152395 | 0.80 | ALDH1A1 (0.43) | ATMALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL27656182 | 0.80 | MARS1 (0.45) | L3MBTL1TP53ALDH1A1MAPTKMT2A | |
| SCHEMBL31031032 | 0.80 | KMT2A (0.45) | RPA1CA1CA2TP53ALDH1A1 | |
| SCHEMBL1063920 | 0.79 | CYP2C9 (0.61) | RPA1L3MBTL1HDAC6ALDH1A1MAPT | |
| SCHEMBL20594704 | 0.79 | IRAK4 (0.44) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL15754423 | 0.78 | RPA1 (0.50) | RPA1L3MBTL1ATMALDH1A1MAPT | |
| SCHEMBL14150735 | 0.78 | KMT2A (0.64) | L3MBTL1ATMMAPTKDM4EMEN1 | |
| SCHEMBL31587169 | 0.77 | AR (0.47) | L3MBTL1ATMABCB11HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092740-A1 | Inhibitors of factor Xa with a neutral P1 specificity group | GALEMMO ROBERT A (US) | 2003-05-15 | — | — | US | disclosed |
| EP-0293220-B1 | Pharmacologically active 2-and 3-substituted (1', 5'-diaryl-3-pyrazolyl)-N-Hydroxypropanamides and method for synthesizing | ORTHO PHARMA CORP (US) | 1994-08-31 | — | — | EP | disclosed |
| US-5051518-A | Antiinflammatory agents and cardiovascular disorders | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092740-A1 | Inhibitors of factor Xa with a neutral P1 specificity group | F12, F11, SERPINC1 | RPA1 506/4885L3MBTL1 2167/4885ATM 4414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.