Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOXO1 | Q12778 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 11/20 | 0.35 |
| ▸ | CNR2 | P34972 | 11/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27656224 | 0.84 | FOXO1 (0.55) | FOXO1MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL4097888 | 0.84 | FOXO1 (0.60) | FOXO1MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL27656223 | 0.83 | MEN1 (0.78) | FOXO1MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL1243848 | 0.82 | FOXO1 (0.58) | FOXO1MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL24063597 | 0.76 | FOXO1 (0.87) | FOXO1MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL27656227 | 0.75 | FOXO1 (0.44) | FOXO1MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL1243931 | 0.74 | FOXO1 (0.66) | FOXO1MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL27656233 | 0.74 | MEN1 (0.60) | FOXO1MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL27735088 | 0.74 | GAA (0.62) | FOXO1MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL1242709 | 0.73 | FOXO1 (0.83) | FOXO1MEN1GAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100471842-C | Carbostyril derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-03-25 | — | — | CN | disclosed |
| CN-1826321-A | Quinolone derivative or its salt | YAMANOUCHI PHARMA CO LTD (JP) | 2006-08-30 | — | — | CN | disclosed |