Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26502145 | 0.73 | — | — | |
| SCHEMBL1493985 | 0.73 | BCL2 (0.33) | AHR | |
| SCHEMBL24592413 | 0.67 | HTR2A (0.38) | — | |
| SCHEMBL24012830 | 0.66 | HTR2A (0.38) | — | |
| SCHEMBL27051566 | 0.66 | HTR2A (0.38) | — | |
| SCHEMBL24253391 | 0.66 | HSP90AB1 (0.40) | — | |
| SCHEMBL24224433 | 0.66 | NOS3 (0.35) | — | |
| SCHEMBL26502144 | 0.65 | KCNA3 (0.38) | — | |
| SCHEMBL1245081 | 0.64 | LMNA (0.42) | AHR | |
| SCHEMBL9861633 | 0.64 | BCL2 (0.46) | AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1930135-B | As P2X3And P2X2/3Diaminopyrimidines as antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-28 | — | — | CN | disclosed |
| CN-1930135-A | As P2X3And P2X2/3Diaminopyrimidines as antagonists | HOFFMANN LA ROCHE (CH) | 2007-03-14 | — | — | CN | disclosed |