Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | SELL | P14151 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15014303 | 0.82 | GABRA1 (0.47) | BCL2BCL2L1MCL1BCL2L2GABRA1 | |
| SCHEMBL2220231 | 0.81 | BCL2 (0.50) | BCL2BCL2L1MCL1BCL2L2GABRA1 | |
| SCHEMBL9008227 | 0.79 | AHR (0.43) | BCL2BCL2L1MCL1BCL2L2GABRA1 | |
| SCHEMBL1245081 | 0.76 | LMNA (0.42) | BCL2BCL2L1MCL1BCL2L2GABRA1 | |
| SCHEMBL6254955 | 0.76 | SELL (0.56) | SELLSELPSELECA1CA2 | |
| SCHEMBL1975537 | 0.74 | LMNA (0.43) | BCL2BCL2L1MCL1BCL2L2GABRA1 | |
| SCHEMBL12572590 | 0.73 | ACHE (0.37) | BCL2BCL2L1MCL1BCL2L2AHR | |
| SCHEMBL1494319 | 0.72 | SELL (0.52) | BCL2BCL2L1MCL1BCL2L2GABRA1 | |
| SCHEMBL23841364 | 0.71 | BCL2 (0.41) | BCL2BCL2L1MCL1BCL2L2GABRA1 | |
| SCHEMBL9862023 | 0.71 | BCL2 (0.50) | BCL2BCL2L1MCL1BCL2L2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032062-B2 | HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |
| EP-0032062-B1 | HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1985-04-03 | — | — | EP | disclosed |
| US-4345054-A | High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| EP-0032062-A2 | High-molecular-weight novolak substituted phenolic resins and their preparation | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1981-07-15 | — | — | EP | disclosed |