Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MGAM | O43451 | 2/20 | 0.50 |
| ▸ | SI | P14410 | 2/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1358344 | 0.82 | ACP1 (0.63) | LMNANPC1SMN1; SMN2RAB9ATP53 | |
| Nitrobenzene SCHEMBL27694792 | 0.82 | NPC1 (0.82) | LMNANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8609550 | 0.80 | FFAR2 (0.67) | LMNANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL24142977 | 0.78 | MEN1 (0.61) | LMNANPC1MAPTKDM4ESMN1; SMN2 | |
| Nitrobenzene SCHEMBL27591249 | 0.77 | NPC1 (0.55) | LMNANPC1MAPTKDM4ESMN1; SMN2 | |
| Nitrobenzene SCHEMBL27714762 | 0.76 | MAPT (0.68) | LMNANPC1MAPTKDM4ERAB9A | |
| Nitrobenzene SCHEMBL27701041 | 0.75 | SMN1; SMN2 (0.52) | LMNANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL3191246 | 0.75 | NPC1 (1.00) | LMNANPC1MAPTKDM4ESMN1; SMN2 | |
| Nitrobenzene SCHEMBL27681966 | 0.74 | NPC1 (0.49) | LMNANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL28010665 | 0.74 | MAPT (0.69) | LMNANPC1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100500665-C | Triazolo-pyrimido-thioacetamide compounds, preparation method and uses | UNIV ZHEJIANG TECHNOLOGY (CN) | 2009-06-17 | — | — | CN | disclosed |
| CN-1962662-A | Triazolo-pyrimido-thioacetamide compounds, preparation method and uses | UNIV ZHEJIANG TECHNOLOGY (CN) | 2007-05-16 | — | — | CN | disclosed |