Styrene

Styrene

SCHEMBL27657397

C1=CCC=C1.C1=CCC=C1.C=Cc1ccccc1.Cc1ccc(O)cc1

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
TSHR P16473 1/20 0.45
ACHE P22303 1/20 0.42
TDP1 Q9NUW8 2/20 0.38
TP53 P04637 1/20 0.38
ESR1 P03372 1/20 0.36
CYP1B1 Q16678 2/20 0.35
MAPT P10636 7/20 0.34
POLB P06746 2/20 0.34
MAOA P21397 2/20 0.34
MAOB P27338 2/20 0.34
RAB9A P51151 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
RRM1 P23921 1/20 0.33
RRM2 P31350 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL28874819 0.94 TSHR (0.45) ALDH1A1TSHRACHETDP1TP53
Styrene SCHEMBL27677421 0.88 ALDH1A1 (0.54) ALDH1A1TSHRTDP1TP53ESR1
Styrene SCHEMBL1824349 0.88 ALDH1A1 (0.58) ALDH1A1TSHRACHETDP1TP53
P-Cresol SCHEMBL28550463 0.84 ACHE (0.54) ALDH1A1TSHRACHETDP1ESR1
Styrene SCHEMBL27598723 0.82 ALDH1A1 (0.67) ALDH1A1TSHRTDP1TP53MAOA
Styrene SCHEMBL21496228 0.82 ALDH1A1 (0.67) ALDH1A1TSHRTDP1TP53MAOA
Styrene SCHEMBL6930140 0.82 ALDH1A1 (0.67) ALDH1A1TSHRTDP1TP53MAOA
Styrene SCHEMBL27657446 0.81 ALDH1A1 (0.45) ALDH1A1TSHRTDP1TP53ESR1
Styrene SCHEMBL26644759 0.80 ALDH1A1 (0.64) ALDH1A1TSHRTDP1TP53MAOB
P-Cresol SCHEMBL216515 0.80 ACHE (0.65) ALDH1A1ACHETDP1ESR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103420810-A Preparation method for polymerization-type asymmetric hindered phenol anti-oxidant resins CHINA PETROLEUM & CHEMICAL 2013-12-04 CN disclosed
CN-103420809-A Preparation method for polymerization-type asymmetric hindered phenol anti-oxidant resins CHINA PETROLEUM & CHEMICAL 2013-12-04 CN disclosed
CN-103319315-A Method for producing aggregate-type hindered phenol antioxidant UNIV HUBEI TECHNOLOGY 2013-09-25 CN disclosed
CN-100424122-C Antioxidant resin through benzene ethylenation of p - methyl phenol - dicyclopentadiene YANWEI YANG (CN) 2008-10-08 CN disclosed
CN-1916060-A Antioxidant resin through benzene ethylenation of p - methyl phenol - dicyclopentadiene YANG YANWEI (CN) 2007-02-21 CN disclosed