Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680435 | 0.86 | MAPT (0.38) | SMN1; SMN2NPC1KDM4EALDH1A1HPGD | |
| SCHEMBL27660494 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1POLBHPGDSIRT1 | |
| SCHEMBL27660446 | 0.65 | MAPT (0.43) | KDM4EALDH1A1ACHESIRT1MAPT | |
| SCHEMBL27567584 | 0.64 | MAPT (0.40) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL726440 | 0.64 | CA1 (0.35) | KDM4EALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL6239976 | 0.61 | CYP3A4 (0.39) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL5532838 | 0.60 | NPC1 (0.44) | SMN1; SMN2NPC1RAB9AKDM4ELMNA | |
| SCHEMBL1165001 | 0.60 | CYP2C19 (0.38) | KMT2AMEN1 | |
| SCHEMBL16109256 | 0.59 | PDE4B (0.53) | SMN1; SMN2NPC1RAB9AKDM4ELMNA | |
| SCHEMBL4226377 | 0.58 | RAB9A (0.57) | SMN1; SMN2NPC1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102697770-A | Murraya paniculata leaf and application of mono compound in preparation of sedative and hypnotic drugs | CHANGCHUN RUIDE MEDICAL TECHNOLOGY CO LTD | 2012-10-03 | — | — | CN | claimed |
| CN-1990482-B | Flavanonol compounds and their production method and use | ZHEJIANG HISUN PHARM CO LTD | 2010-12-08 | — | — | CN | claimed |
| CN-1990482-A | Flavanonol compounds and their production method and use | ZHEJIANG HISUN NATURELITE PHAR (CN) | 2007-07-04 | — | — | CN | claimed |
| CN-102697770-A | Murraya paniculata leaf and application of mono compound in preparation of sedative and hypnotic drugs | CHANGCHUN RUIDE MEDICAL TECHNOLOGY CO LTD | 2012-10-03 | — | — | CN | disclosed |
| CN-102669195-A | Method for extracting total flavonoids from murraya paniculata stems and leaves | UNIV HAINAN | 2012-09-19 | — | — | CN | disclosed |
| CN-1990482-B | Flavanonol compounds and their production method and use | ZHEJIANG HISUN PHARM CO LTD | 2010-12-08 | — | — | CN | disclosed |
| CN-1990482-A | Flavanonol compounds and their production method and use | ZHEJIANG HISUN NATURELITE PHAR (CN) | 2007-07-04 | — | — | CN | disclosed |