SCHEMBL27680435

SCHEMBL27680435

COc1cc2c(c(OC)c1OC)C(=O)C(OC)(OC)C(OC)(c1ccccc1)O2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
XDH P47989 1/20 0.35
ALDH1A1 P00352 4/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
CA13 Q8N1Q1 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HTR6 P50406 1/20 0.34
CYP3A4 P08684 1/20 0.34
SIRT1 Q96EB6 3/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27660464 0.86 SMN1; SMN2 (0.39) MAPTMEN1KMT2ATDP1ALDH1A1
SCHEMBL27660494 0.81 KDM4E (0.40) MAPTMEN1KMT2ANPSR1TDP1
SCHEMBL27660446 0.79 MAPT (0.43) MAPTMEN1GAAKMT2ANPSR1
SCHEMBL28524099 0.72 STK17B (0.36) MAPTMEN1GAAKMT2ANPSR1
SCHEMBL27680430 0.71 XDH (0.48) MAPTMEN1GAAKMT2ANPSR1
SCHEMBL29358153 0.68 ALDH1A1 (0.41) MAPTMEN1GAAKMT2ATDP1
SCHEMBL7739870 0.68 EDNRB (0.41) MAPTMEN1GAAKMT2ANPSR1
SCHEMBL27660441 0.66 XDH (0.47) MAPTMEN1GAAKMT2ANPSR1
SCHEMBL29500460 0.64 RIPK1 (0.53) MAPTMEN1GAAKMT2ANPSR1
SCHEMBL28760424 0.63 XDH (0.52) MAPTMEN1GAAKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1990482-B Flavanonol compounds and their production method and use ZHEJIANG HISUN PHARM CO LTD 2010-12-08 CN claimed
CN-1990482-A Flavanonol compounds and their production method and use ZHEJIANG HISUN NATURELITE PHAR (CN) 2007-07-04 CN claimed
CN-104771601-A Combination agent for improving blood viscosity and platelet aggregation ZHANG KUNYONG 2015-07-15 CN disclosed
CN-1990482-B Flavanonol compounds and their production method and use ZHEJIANG HISUN PHARM CO LTD 2010-12-08 CN disclosed
CN-101543281-A Cooking spray and preparation method thereof XUSHAN WAN 2009-09-30 CN disclosed
CN-1990482-A Flavanonol compounds and their production method and use ZHEJIANG HISUN NATURELITE PHAR (CN) 2007-07-04 CN disclosed