Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680816 | 0.88 | SRD5A1 (0.33) | KDM1AMDM2 | |
| SCHEMBL27660901 | 0.88 | SRD5A1 (0.33) | KDM1AMDM2 | |
| SCHEMBL5709412 | 0.87 | KDM1A (0.38) | KDM1AALOX5LTB4RLTB4R2MAOB | |
| SCHEMBL27660699 | 0.82 | TP53 (0.35) | MDM2 | |
| SCHEMBL27680721 | 0.82 | TP53 (0.35) | MDM2 | |
| SCHEMBL27660891 | 0.82 | BCHE (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL5709462 | 0.81 | KDM1A (0.45) | KDM1AMAOBMAOAFFAR1AR | |
| SCHEMBL5709411 | 0.77 | LTA4H (0.38) | KDM1AHIF1AAR | |
| SCHEMBL5709377 | 0.76 | FFAR1 (0.44) | KDM1AMAOBMAOAFFAR1 | |
| SCHEMBL5709474 | 0.75 | AR (0.40) | KDM1AMAOBFFAR1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950328-A | Phenyl indan derivatives | LUNDBECK & CO AS H (DK) | 2007-04-18 | — | — | CN | disclosed |