Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 3/20 | 0.42 |
| ▸ | RXRB | P28702 | 3/20 | 0.42 |
| ▸ | RXRG | P48443 | 3/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709474 | 0.90 | AR (0.40) | KDM1ARXRARXRBRXRGMRGPRX4 | |
| SCHEMBL5709377 | 0.90 | FFAR1 (0.44) | KDM1ARXRARXRBRXRGMRGPRX4 | |
| SCHEMBL5709343 | 0.86 | KDM1A (0.46) | KDM1ARXRARXRBRXRGMRGPRX4 | |
| SCHEMBL5709371 | 0.85 | KDM1A (0.47) | KDM1AMAOBMAOASIGMAR1HRH3 | |
| SCHEMBL27660700 | 0.84 | HSD11B1 (0.42) | KDM1ASIGMAR1ALDH1A1 | |
| SCHEMBL5709364 | 0.84 | HSD11B1 (0.42) | KDM1ASIGMAR1ALDH1A1 | |
| SCHEMBL27680729 | 0.84 | HSD11B1 (0.42) | KDM1ASIGMAR1ALDH1A1 | |
| SCHEMBL5709523 | 0.84 | KCNA5 (0.45) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL5709411 | 0.82 | LTA4H (0.38) | KDM1ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5709412 | 0.82 | KDM1A (0.38) | KDM1ARXRARXRBRXRGMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950328-A | Phenyl indan derivatives | LUNDBECK & CO AS H (DK) | 2007-04-18 | — | — | CN | disclosed |
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |