SCHEMBL27660935

SCHEMBL27660935

Cl[Si](Cl)(Cl)c1cccc(Oc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.50
TSHR P16473 1/20 0.50
MAOB P27338 1/20 0.50
AKR1C3 P42330 1/20 0.46
MITF O75030 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
GFER P55789 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NLRP1 Q9C000 1/20 0.42
NOD2 Q9HC29 1/20 0.42
HDAC8 Q9BY41 1/20 0.41
POLB P06746 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
NR1H2 P55055 1/20 0.40
BAX Q07812 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5656129 0.84 MAOB (0.47) LTA4HTSHRMAOBAKR1C3MITF
SCHEMBL30407753 0.84 MAOB (0.47) LTA4HTSHRMAOBAKR1C3MITF
SCHEMBL28558458 0.81 LTA4H (0.52) LTA4HTSHRMAOBAKR1C3MITF
SCHEMBL5485054 0.80 LTA4H (0.57) LTA4HTSHRMEN1KMT2ANR1H2
SCHEMBL30211827 0.77 LTA4H (0.75) LTA4HTSHRMAOBAKR1C3MITF
SCHEMBL30018242 0.77 LTA4H (0.75) LTA4HTSHRMAOBAKR1C3MITF
SCHEMBL22559 0.77 LTA4H (0.75) LTA4HTSHRMAOBAKR1C3MITF
SCHEMBL380685 0.77 LTA4H (0.75) LTA4HTSHRMAOBAKR1C3MITF
SCHEMBL1173711 0.77 LTA4H (0.75) LTA4HTSHRMAOBAKR1C3MITF
SCHEMBL4025817 0.77 LTA4H (0.75) LTA4HTSHRMAOBAKR1C3MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1989081-B Method of reforming interlayer film for heat-insulating laminated glass SEKISUI CHEMICAL CO LTD 2010-12-15 CN disclosed
CN-1989081-A Method of reforming interlayer film for heat-insulating laminated glass SEKISUI CHEMICAL CO LTD (JP) 2007-06-27 CN disclosed