Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1751870 | 0.85 | MAPT (0.42) | KCNJ1KCNH2HRH3MAPTMAOA | |
| SCHEMBL14790114 | 0.76 | KCNJ1 (0.53) | KCNJ1KCNH2HRH3MAPTMAOA | |
| SCHEMBL14785737 | 0.72 | KCNJ1 (0.72) | KCNJ1KCNH2HRH3MAOASIGMAR1 | |
| SCHEMBL15954217 | 0.70 | HTT (0.54) | KCNJ1KCNH2HRH3MAPTALDH1A1 | |
| SCHEMBL18280033 | 0.68 | ALDH1A1 (0.51) | MAPTMAOAALDH1A1ACHE | |
| SCHEMBL15964106 | 0.68 | KCNJ1 (0.56) | KCNJ1KCNH2HRH3MAOA | |
| SCHEMBL14782744 | 0.68 | ALDH1A1 (0.60) | MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL14783255 | 0.67 | KCNJ1 (0.55) | KCNJ1KCNH2HRH3MAOA | |
| SCHEMBL28777622 | 0.64 | SIGMAR1 (0.58) | KCNJ1MAPTALDH1A1ACHESIGMAR1 | |
| SCHEMBL25189631 | 0.63 | MEN1 (0.60) | HRH3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1887875-A | Pyridazinamine derivative and application thereof in preparing small RNA virus inhibitor | INST OF TOXICANT PHARMACOLOGY (CN) | 2007-01-03 | — | — | CN | claimed |
| CN-1887875-B | Pyridazinamine derivative and application thereof in preparing small RNA virus inhibitor | SHENZHEN DONG YANGGUANG IND DEV CO LTD | 2011-04-06 | — | — | CN | disclosed |
| CN-1887875-A | Pyridazinamine derivative and application thereof in preparing small RNA virus inhibitor | INST OF TOXICANT PHARMACOLOGY (CN) | 2007-01-03 | — | — | CN | disclosed |