SCHEMBL2766136

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2763878	0.87	AHR (0.55)	AHRTTRMCL1CA1CA2
	SCHEMBL22737968	0.82	AHR (0.78)	AHRTTRMCL1CDC25ACDC25C
	SCHEMBL1461411	0.82	KDM4E (0.33)	KDM4EALDH1A1LMNAMAPTALOX15
	SCHEMBL7414141	0.78	TTR (0.54)	AHRTTRCA1CA2DAO
	SCHEMBL21295744	0.78	MAOB (0.45)	CDC25ACDC25CPSMB8KDM4EALDH1A1
	SCHEMBL20209148	0.78	AHR (0.72)	AHRTTRMCL1CDC25ACDC25C
	SCHEMBL30170495	0.78	AHR (0.72)	AHRTTRMCL1CDC25ACDC25C
	SCHEMBL20208918	0.78	AHR (0.72)	AHRTTRMCL1CDC25ACDC25C
	SCHEMBL22078192	0.76	AHR (0.69)	AHRTTRMCL1CDC25ACDC25C
	SCHEMBL1927485	0.74	AHR (0.56)	AHRTTRMCL1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.