Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 3/20 | 0.55 |
| ▸ | MMP9 | P14780 | 3/20 | 0.55 |
| ▸ | MMP14 | P50281 | 3/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13864744 | 0.93 | HDAC2 (0.58) | BMP1MMP2MMP9MMP14MMP8 | |
| SCHEMBL27662336 | 0.92 | HDAC8 (0.58) | MMP2MMP9MMP14MMP8MMP12 | |
| SCHEMBL27662300 | 0.92 | MMP9 (0.67) | MMP2MMP9MMP14MMP8MMP12 | |
| SCHEMBL27662296 | 0.91 | MMP2 (0.56) | MMP2MMP9MMP14MMP8MMP12 | |
| SCHEMBL27681821 | 0.90 | ALDH1A1 (0.63) | MMP2MMP9MMP14MMP8MMP12 | |
| SCHEMBL28760853 | 0.90 | MMP2 (0.55) | MMP2MMP9MMP14MMP8MMP12 | |
| SCHEMBL27681827 | 0.89 | HDAC8 (0.50) | BMP1MMP2MMP9MMP14MMP8 | |
| SCHEMBL27681824 | 0.87 | HDAC8 (0.55) | MMP2MMP9MMP14MMP8MMP12 | |
| SCHEMBL28760860 | 0.87 | MMP2 (0.53) | MMP2MMP9MMP14MMP8MMP12 | |
| SCHEMBL27662302 | 0.86 | HDAC8 (0.51) | MMP2MMP9MMP14MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1997625-A | Histone deacetylase inhibitors | MERCK & CO INC (US) | 2007-07-11 | — | — | CN | claimed |
| CN-1997625-A | Histone deacetylase inhibitors | MERCK & CO INC (US) | 2007-07-11 | — | — | CN | disclosed |