Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.43 |
| ▸ | PARN | O95453 | 1/20 | 0.43 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29044749 | 0.80 | KDM4C (0.48) | MAPK14CYP11B2TNFCYP11B1GAA | |
| SCHEMBL3525336 | 0.80 | ADORA2A (0.51) | MAPK14CYP11B2TNFCYP11B1GAA | |
| SCHEMBL3523300 | 0.80 | GAA (0.50) | MAPK14CYP11B2TNFCYP11B1GAA | |
| SCHEMBL1529051 | 0.80 | YTHDC1 (0.46) | MAPK14CYP11B2TNFCYP11B1GAA | |
| SCHEMBL3521393 | 0.76 | MAPK14 (0.58) | MAPK14CYP11B2TNFCYP11B1GAA | |
| SCHEMBL11788419 | 0.76 | PKM (0.45) | MAPK14CYP11B2TNFCYP11B1GAA | |
| SCHEMBL3519184 | 0.75 | MAPK14 (0.50) | MAPK14CYP11B2TNFCYP11B1GAA | |
| SCHEMBL3518913 | 0.75 | ABL1 (0.51) | MAPK14CYP11B2TNFCYP11B1GAA | |
| SCHEMBL3522628 | 0.73 | MAPK14 (0.51) | MAPK14CYP11B2CYP11B1GAAPKM | |
| SCHEMBL6472397 | 0.72 | MAPK14 (0.58) | MAPK14ADORA2ASMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1968937-A | Pyrimidin-4-one derivatives and their use as P38 kinase modulators | PHARMACIA CORP (US) | 2007-05-23 | — | — | CN | disclosed |