Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.43 |
| ▸ | PARN | O95453 | 1/20 | 0.43 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3525336 | 0.80 | ADORA2A (0.51) | KDM4CMAPK14CYP11B2TNFCYP11B1 | |
| SCHEMBL3523300 | 0.80 | GAA (0.50) | KDM4CMAPK14CYP11B2TNFCYP11B1 | |
| SCHEMBL27663449 | 0.80 | MAPK14 (0.48) | KDM4CMAPK14CYP11B2TNFCYP11B1 | |
| SCHEMBL3521393 | 0.76 | MAPK14 (0.58) | MAPK14CYP11B2TNFCYP11B1GAA | |
| SCHEMBL1529051 | 0.76 | YTHDC1 (0.46) | MAPK14CYP11B2TNFCYP11B1GAA | |
| SCHEMBL11788419 | 0.76 | PKM (0.45) | KDM4CMAPK14CYP11B2TNFCYP11B1 | |
| SCHEMBL3522628 | 0.76 | MAPK14 (0.51) | MAPK14CYP11B2CYP11B1GAAPKM | |
| SCHEMBL3519184 | 0.75 | MAPK14 (0.50) | KDM4CMAPK14CYP11B2TNFCYP11B1 | |
| SCHEMBL3518913 | 0.75 | ABL1 (0.51) | MAPK14CYP11B2TNFCYP11B1GAA | |
| SCHEMBL20936157 | 0.72 | MAPK14 (0.58) | MAPK14ADORA2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035349-A1 | 3,4-alkoxy Substituted Phenethyl Lactam Compound, Preparation Method therefor, and Use Thereof | GUANGZHOU CHIA TAI INNOVATIVE PHARMACEUTICAL CO., LTD. (CN) | 2026-02-05 | — | — | US | disclosed |
| CN-116535350-A | 3, 4-alkoxy substituted phenethyl lactam compound, and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-08-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035349-A1 | 3,4-alkoxy Substituted Phenethyl Lactam Compound, Preparation Method therefor, and Use Thereof | CES1, CYP51A1, PDE3A | KDM4C 891/4885MAPK14 3034/4885CYP11B2 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.