SCHEMBL27664166

SCHEMBL27664166

c1coc(-c2nc(C3=NCCO3)co2)n1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1920363 0.81 LTA4H (0.36) LTA4H
SCHEMBL27584843 0.70
SCHEMBL4453820 0.69 HPGDS (0.51) LTA4H
SCHEMBL13140577 0.68
Hydrochloric Acid SCHEMBL7179476 0.67 KDM4E (0.42) LTA4H
Hydrochloric Acid SCHEMBL7182447 0.67 KDM4E (0.42) LTA4H
SCHEMBL100765 0.66 HPGDS (0.46) LTA4H
SCHEMBL8741062 0.65 AOC3 (0.35) LTA4H
Hydrochloric Acid SCHEMBL7180629 0.64 KDM4E (0.42) LTA4H
Hydrochloric Acid SCHEMBL7174198 0.64 KDM4E (0.42) LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1984904-A 3-aryl-5,6-disubstituted pyridazines NEUROGEN CORP (US) 2007-06-20 CN disclosed