Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.41 |
| ▸ | RBP4 | P02753 | 5/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781323 | 0.89 | DRD3 (0.45) | DRD2RBP4HRH2DRD3SLC6A4 | |
| SCHEMBL27664533 | 0.85 | RBP4 (0.40) | DRD2RBP4HRH2HTR7DRD3 | |
| SCHEMBL2781711 | 0.82 | DRD3 (0.43) | DRD2RBP4DRD3HTR2ASLC6A4 | |
| SCHEMBL2783245 | 0.81 | RBP4 (0.40) | DRD2RBP4HRH2DRD3HTR2A | |
| SCHEMBL2781420 | 0.81 | HRH2 (0.47) | DRD2RBP4HRH2DRD3HTR2A | |
| SCHEMBL2782067 | 0.81 | HTR1A (0.40) | DRD2RBP4HRH2HTR7DRD3 | |
| SCHEMBL2781921 | 0.80 | HRH2 (0.49) | DRD2RBP4HRH2DRD3HTR2A | |
| SCHEMBL2783115 | 0.80 | MAP3K12 (0.45) | DRD2RBP4DRD3HTR2ASLC6A4 | |
| SCHEMBL2782819 | 0.79 | DRD2 (0.41) | DRD2RBP4HRH2HTR7DRD3 | |
| SCHEMBL2783595 | 0.78 | RBP4 (0.58) | DRD2RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1997630-A | New disubstituted phenylpiperidines as modulators of dopamine neurotransmission | NEUROSEARCH SWEDEN AB (SE) | 2007-07-11 | — | — | CN | claimed |
| CN-1997630-B | New disubstituted phenylpiperidines as modulators of dopamine neurotransmission | NEUROSEARCH SWEDEN AB | 2013-01-30 | — | — | CN | disclosed |
| CN-1997630-A | New disubstituted phenylpiperidines as modulators of dopamine neurotransmission | NEUROSEARCH SWEDEN AB (SE) | 2007-07-11 | — | — | CN | disclosed |