Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456912 | 0.82 | MAOB (0.55) | ALOX5MAOBCYP3A4CA12CA1 | |
| SCHEMBL9136135 | 0.81 | ALOX5 (0.58) | ALOX5MAOBCYP3A4CA12CA1 | |
| SCHEMBL27970437 | 0.81 | ALOX5 (0.58) | ALOX5MAOBCYP3A4CA12CA1 | |
| SCHEMBL27643424 | 0.81 | ALOX5 (0.58) | ALOX5MAOBCYP3A4CA12CA1 | |
| SCHEMBL6172684 | 0.80 | ALOX5 (0.54) | ALOX5MAOBCYP3A4CA12CA1 | |
| SCHEMBL7455290 | 0.80 | MAOB (0.55) | ALOX5MAOBCYP3A4NPC1SCD | |
| SCHEMBL6807350 | 0.79 | ALOX5 (0.57) | ALOX5MAOBCYP3A4CA12CA1 | |
| SCHEMBL3745463 | 0.79 | CYP3A4 (0.50) | ALOX5MAOBCYP3A4CA12CA1 | |
| SCHEMBL30430896 | 0.78 | ALOX5 (0.55) | ALOX5MAOBCYP3A4CA12CA1 | |
| SCHEMBL5442084 | 0.78 | ALOX5 (0.55) | ALOX5MAOBCYP3A4CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1890221-B | 1-N-phenyl-amino-1H-imidazole derivatives and pharmaceutical compositions containing them | THERAMEX | 2014-07-16 | — | — | CN | disclosed |
| CN-1890221-A | 1-N-phenyl-amino-1H-imidazole derivatives and pharmaceutical compositions containing them | THERAMEX (MC) | 2007-01-03 | — | — | CN | disclosed |