Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 6/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | TOP1 | P11387 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136526 | 0.82 | RXRA (0.49) | ALOX5MAOBMAOACYP3A4NPC1 | |
| SCHEMBL27664686 | 0.81 | ALOX5 (0.57) | ALOX5MAOBMAOACYP3A4CA12 | |
| SCHEMBL27970437 | 0.79 | ALOX5 (0.58) | ALOX5MAOBMAOACYP3A4CA12 | |
| SCHEMBL27643424 | 0.79 | ALOX5 (0.58) | ALOX5MAOBMAOACYP3A4CA12 | |
| SCHEMBL5452956 | 0.78 | ALOX5 (0.54) | ALOX5MAOBMAOACYP3A4CA12 | |
| SCHEMBL17347192 | 0.78 | NR4A2 (0.54) | ALOX5CYP3A4CA12CA9CA1 | |
| SCHEMBL5444314 | 0.78 | MRGPRX4 (0.69) | ALOX5MAOBMAOACYP3A4CA12 | |
| SCHEMBL6807350 | 0.78 | ALOX5 (0.57) | ALOX5MAOBMAOACYP3A4CA12 | |
| SCHEMBL30430896 | 0.77 | ALOX5 (0.55) | ALOX5MAOBMAOACYP3A4CA12 | |
| SCHEMBL5442084 | 0.77 | ALOX5 (0.55) | ALOX5MAOBMAOACYP3A4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414006-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |