Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | F9 | P00740 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30430896 | 0.96 | ALOX5 (0.55) | ALOX5ESR1ESR2CYP3A4CA12 | |
| SCHEMBL7453943 | 0.92 | ESR1 (0.58) | ALOX5ESR1ESR2CYP3A4CA12 | |
| SCHEMBL17845134 | 0.91 | MAOB (0.51) | ALOX5ESR1ESR2CYP3A4CA12 | |
| SCHEMBL7456912 | 0.91 | MAOB (0.55) | ALOX5ESR1ESR2CYP3A4CA12 | |
| SCHEMBL7455290 | 0.88 | MAOB (0.55) | ALOX5ESR1ESR2CYP3A4F9 | |
| SCHEMBL21906717 | 0.87 | MRGPRX4 (0.47) | ALOX5ESR1ESR2CYP3A4CA12 | |
| SCHEMBL7452873 | 0.85 | CA12 (0.47) | ALOX5ESR1ESR2CYP3A4CA12 | |
| SCHEMBL27970437 | 0.81 | ALOX5 (0.58) | ALOX5CYP3A4CA12CA1CA2 | |
| SCHEMBL27643424 | 0.81 | ALOX5 (0.58) | ALOX5CYP3A4CA12CA1CA2 | |
| SCHEMBL27664686 | 0.79 | ALOX5 (0.57) | ALOX5CYP3A4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044224-A1 | Process for preparing 2-phenyl-3-aminobenzothiophenes | CONRAD PRESTON CHARLES (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044224-A1 | Process for preparing 2-phenyl-3-aminobenzothiophenes | TPST2, SULT1A1, TYR | ALOX5 2246/4885ESR1 4153/4885ESR2 3952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.