Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613084 | 1.00 | RAB9A (0.48) | RAB9ANPC1TSHRALDH1A1GAA | |
| SCHEMBL613561 | 0.91 | NPC1 (0.49) | RAB9ANPC1TSHRGAASMN1; SMN2 | |
| SCHEMBL610160 | 0.90 | DGAT2 (0.45) | RAB9ANPC1TSHRALDH1A1GAA | |
| SCHEMBL613039 | 0.88 | USP30 (0.48) | TSHRALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL612692 | 0.87 | GPBAR1 (0.49) | TSHRGAAPOLBHSD17B10KMT2A | |
| SCHEMBL4962181 | 0.87 | GPBAR1 (0.49) | TSHRGAAPOLBHSD17B10KMT2A | |
| SCHEMBL613617 | 0.86 | KMT2A (0.47) | RAB9ANPC1TSHRALDH1A1GAA | |
| SCHEMBL4960299 | 0.86 | KMT2A (0.47) | RAB9ANPC1TSHRALDH1A1GAA | |
| SCHEMBL612641 | 0.85 | RET (0.54) | — | |
| SCHEMBL612737 | 0.83 | RAB9A (0.47) | RAB9ANPC1TSHRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1993128-A | N-substituted piperidines and their use as pharmaceuticals | INCYTE CORP (US) | 2007-07-04 | — | — | CN | claimed |
| CN-1993128-A | N-substituted piperidines and their use as pharmaceuticals | INCYTE CORP (US) | 2007-07-04 | — | — | CN | disclosed |