Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665532 | 0.86 | TSHR (0.45) | NPC1RAB9ASMN1; SMN2HIF1ABLM | |
| SCHEMBL27665625 | 0.85 | PNMT (0.50) | PKMCYP1A2 | |
| SCHEMBL27665810 | 0.84 | GRB2 (0.43) | BLMMEN1KMT2ACYP1A2 | |
| SCHEMBL27644132 | 0.83 | HTR2A (0.55) | SLC6A2SLC6A4SLC6A3SIGMAR1CYP1A2 | |
| SCHEMBL27644420 | 0.82 | SMN1; SMN2 (0.40) | NPC1RAB9ASMN1; SMN2HIF1AALPI | |
| SCHEMBL27665702 | 0.78 | RIPK1 (0.61) | TAAR1BLMCYP1A2CYP2D6 | |
| SCHEMBL3616371 | 0.76 | GRM2 (0.51) | NPC1RAB9ASMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL202819 | 0.76 | GRM2 (0.51) | NPC1RAB9ASMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL27748006 | 0.76 | GRM2 (0.51) | NPC1RAB9ASMN1; SMN2HIF1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL1807415 | 0.75 | GRM2 (0.50) | NPC1RAB9ASMN1; SMN2HIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |