Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27644221 | 0.84 | ALDH1A1 (0.43) | RIPK1CYP2C19 | |
| SCHEMBL27665501 | 0.83 | GRM8 (0.43) | RIPK1CYP2D6CNR2 | |
| SCHEMBL27665568 | 0.82 | PNMT (0.46) | RIPK1CYP1A2 | |
| SCHEMBL23009730 | 0.81 | RIPK1 (0.40) | RIPK1CYP1A2CYP2D6GGT1BLM | |
| SCHEMBL27665641 | 0.78 | NPC1 (0.42) | TAAR1CYP1A2CYP2D6BLM | |
| SCHEMBL28053807 | 0.77 | RIPK1 (0.56) | RIPK1TAAR1CYP1A2CYP2D6TRPA1 | |
| SCHEMBL27665532 | 0.76 | TSHR (0.45) | CYP1A2BLMCYP2C19 | |
| SCHEMBL27741015 | 0.76 | RIPK1 (0.60) | RIPK1TAAR1CYP1A2CYP2D6TRPA1 | |
| SCHEMBL22290856 | 0.76 | MMP8 (0.43) | CYP1A2CYP2D6 | |
| SCHEMBL14278978 | 0.75 | RIPK1 (0.54) | RIPK1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |