Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | NPC1 | O15118 | 7/20 | 0.73 |
| ▸ | MAPT | P10636 | 7/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.71 |
| ▸ | RELA | Q04206 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994898 | 0.85 | MAPT (1.00) | RAB9ANPC1MAPTHPGDHTT | |
| SCHEMBL1993946 | 0.85 | NPC1 (1.00) | RAB9ANPC1MAPTHPGDHTT | |
| SCHEMBL1997356 | 0.85 | RAB9A (0.73) | RAB9ANPC1MAPTHPGDHTT | |
| SCHEMBL1993758 | 0.85 | RAB9A (0.73) | RAB9ANPC1MAPTHPGDHTT | |
| SCHEMBL1993042 | 0.84 | RAB9A (1.00) | RAB9ANPC1MAPTHPGDHTT | |
| SCHEMBL1994550 | 0.80 | PTGDR2 (0.78) | RAB9ANPC1MAPTHTTSMN1; SMN2 | |
| SCHEMBL7729542 | 0.79 | HPGDS (0.79) | RAB9ANPC1MAPTHPGDHTT | |
| SCHEMBL28761479 | 0.78 | MAPT (0.67) | RAB9ANPC1MAPTHPGDHTT | |
| SCHEMBL5194327 | 0.77 | ALDH1A1 (0.63) | MAPTHPGDMEN1KMT2AGAA | |
| SCHEMBL1990486 | 0.73 | RAB9A (0.62) | RAB9ANPC1MAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980664-B | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS | 2011-02-23 | — | — | CN | disclosed |
| CN-1980664-A | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS (DK) | 2007-06-13 | — | — | CN | disclosed |