Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2943836 | 0.75 | SLC6A4 (0.64) | CHKACHRNA7 | |
| SCHEMBL27666179 | 0.70 | RAB9A (0.62) | — | |
| SCHEMBL10482671 | 0.69 | DRD4 (0.55) | HTR1A | |
| SCHEMBL2087118 | 0.69 | PDE4A (0.51) | — | |
| SCHEMBL682635 | 0.69 | PDE4A (0.51) | — | |
| SCHEMBL2085028 | 0.69 | PDE4A (0.50) | NR1H2NR1H3 | |
| SCHEMBL682509 | 0.69 | PDE4A (0.50) | NR1H2NR1H3 | |
| SCHEMBL4208987 | 0.69 | CHRNA7 (0.52) | HTR1ACHRNA7ACACB | |
| SCHEMBL28874935 | 0.68 | TERT (0.56) | HTR1ACHRNA7 | |
| SCHEMBL8697900 | 0.68 | NR1H2 (0.49) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |