Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116079 | 0.75 | MEN1 (0.49) | DRD4LMNASLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL9597674 | 0.73 | HSD11B1 (0.46) | DRD4LMNANR1I2ADORA3CNR1 | |
| SCHEMBL9595506 | 0.70 | SIGMAR1 (0.55) | NR1H2NR1H3DRD4ALDH1A1 | |
| SCHEMBL9594834 | 0.70 | DRD4 (0.50) | NR1H2NR1H3DRD4 | |
| SCHEMBL18965735 | 0.69 | DRD4 (0.70) | DRD4LMNANR1I2ADORA3CNR1 | |
| SCHEMBL27666153 | 0.68 | NR1H2 (0.44) | NR1H2NR1H3 | |
| SCHEMBL31598338 | 0.68 | — | — | |
| SCHEMBL11480291 | 0.68 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL19001026 | 0.68 | OPRM1 (0.41) | HSD11B1 | |
| SCHEMBL16569821 | 0.68 | DRD4 (0.41) | NR1H2NR1H3DRD4LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792770-A | ADMINISTERING AS SEDATIVE, TRANQUILIZER, ANXIOLYTIC AGENT | U C B S.A. (BE) | 1998-08-11 | — | — | US | disclosed |
| US-5703082-A | ANTIHISTAMINE; TRANQUILIZERS | U C B S.A. (BE) | 1997-12-30 | — | — | US | disclosed |