Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 8/20 | 0.44 |
| ▸ | THRB | P10828 | 8/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12824842 | 0.85 | MEN1 (0.51) | SLC7A5MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL27053517 | 0.81 | MEN1 (0.48) | SLC7A5MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL12824843 | 0.79 | THRA (0.46) | SLC7A5MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL281929 | 0.79 | THRA (0.63) | SLC7A5MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL29373597 | 0.78 | THRB (0.69) | SLC7A5THRATHRB | |
| SCHEMBL3341367 | 0.78 | THRB (0.69) | SLC7A5THRATHRB | |
| SCHEMBL19508336 | 0.77 | THRB (0.54) | SLC7A5MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL12824840 | 0.77 | THRB (0.57) | SLC7A5MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL10886054 | 0.76 | IDH1 (0.70) | SLC7A5MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL9173452 | 0.76 | IDH1 (0.70) | SLC7A5MEN1KMT2ACYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101180097-A | Novel phosphinic acid-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2008-05-14 | — | — | CN | disclosed |
| CN-1882327-A | Novel phosphorus-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2006-12-20 | — | — | CN | disclosed |