SCHEMBL3341367

SCHEMBL3341367

Cc1cc(OCC(=O)O)cc(C)c1Cc1ccc(O)c(Cc2ccccc2)c1

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 19/20 0.69
THRA P10827 18/20 0.69
SLC7A5 Q01650 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373597 1.00 THRB (0.69) THRBTHRASLC7A5
SCHEMBL23003762 0.91 THRB (0.66) THRBTHRA
SCHEMBL20601960 0.87 THRB (0.67) THRBTHRA
SCHEMBL23003728 0.86 THRB (0.65) THRBTHRASLC7A5
SCHEMBL19508336 0.85 THRB (0.54) THRBTHRASLC7A5
SCHEMBL12824840 0.85 THRB (0.57) THRBTHRASLC7A5
SCHEMBL23003721 0.84 THRB (0.57) THRBTHRA
Vk-0214 SCHEMBL283442 0.84 THRB (0.79) THRBTHRASLC7A5
SCHEMBL25856594 0.83 THRB (0.67) THRBTHRASLC7A5
SCHEMBL22071776 0.82 THRB (0.62) THRBTHRASLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260053761-A1 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER UNIV OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2026-02-26 US claimed
EP-4561704-A2 USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2025-06-04 EP claimed
WO-2024026458-A2 USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER THE UNIVERSITY OF VERMONT (US) 2024-02-01 WO claimed
US-20230255974-A1 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE 2023-08-17 US claimed
EP-4110344-A2 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2023-01-04 EP claimed
US-20260053761-A1 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER UNIV OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2026-02-26 US disclosed
EP-4561704-A2 USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2025-06-04 EP disclosed
US-11969501-B2 Auris formulations for treating otic diseases and conditions DOMPÉ FARMACEUTICI S.P.A. (IT) 2024-04-30 US disclosed
US-11918653-B2 Triglyceride otic formulations and uses thereof DOMPÉ FARMACEUTICI S.P.A. (IT) 2024-03-05 US disclosed
WO-2024026458-A2 USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER THE UNIVERSITY OF VERMONT (US) 2024-02-01 WO disclosed
US-20230255974-A1 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE 2023-08-17 US disclosed
EP-4110344-A2 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2023-01-04 EP disclosed
US-20100021416-A1 CONTROLLED-RELEASE OTIC STRUCTURE MODULATING AND INNATE IMMUNE SYSTEM MODULATING COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS OTONOMY, INC. (US) 2010-01-28 US disclosed
US-20100015263-A1 CONTROLLED RELEASE AURIS SENSORY CELL MODULATOR COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS OTONOMY, INC. (US) 2010-01-21 US disclosed
US-20090306225-A1 AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS OTONOMY, INC. (US) 2009-12-10 US disclosed
US-7302347-B2 Method for creating specific, high affinity nuclear receptor pharmaceuticals THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-11-27 US disclosed
US-7302347-B2 Method for creating specific, high affinity nuclear receptor pharmaceuticals THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-11-27 US disclosed
US-20040253648-A1 Method for creating nuclear receptor activity modulating pharmaceuticals THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-12-16 US disclosed
WO-2004052303-A2 A METHOD FOR CREATING NUCLEAR RECEPTOR ACTIVITY MODULATING PHARMACEUTICALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-06-24 WO disclosed
WO-2004052302-A2 A METHOD FOR CREATING SPECIFIC, HIGH AFFINITY NUCLEAR RECEPTOR PHARMACEUTICALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100015263-A1 CONTROLLED RELEASE AURIS SENSORY CELL MODULATOR COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS OTC, MYOC, S100B THRB 1555/4885THRA 1522/4885SLC7A5 2150/4885
US-20260053761-A1 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER THRA, THRB, TRHR THRB 2/4885THRA 1/4885SLC7A5 3427/4885
US-20090306225-A1 AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS OTC, AQP4, SLC26A4 THRB 3286/4885THRA 1945/4885SLC7A5 981/4885
US-11918653-B2 Triglyceride otic formulations and uses thereof CETP, LIPA, APOB THRB 429/4885THRA 311/4885SLC7A5 1350/4885
US-20100021416-A1 CONTROLLED-RELEASE OTIC STRUCTURE MODULATING AND INNATE IMMUNE SYSTEM MODULATING COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS OTC, TLR3, STING1 THRB 2404/4885THRA 1919/4885SLC7A5 1657/4885
US-11969501-B2 Auris formulations for treating otic diseases and conditions OTC, AQP4, SLC26A4 THRB 3286/4885THRA 1945/4885SLC7A5 981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.